Which cells secrete antibodies during the immune response?

• A. T cells
• B. Macrophages
• C. B cells
• D. Dendritic cells

Answer: (C)

Antibody production comes from B cells that differentiate into antibody-secreting plasma cells as part of the humoral immune response. When a B cell recognizes an antigen and receives help from helper T cells, it proliferates and becomes a plasma cell that releases large amounts of antibodies into blood and tissues. These antibodies neutralize pathogens and flag them for attack by other immune cells. Other immune cells don’t secrete antibodies: T cells coordinate and execute cell-mediated responses, while macrophages and dendritic cells are antigen-presenting cells that process antigens and activate T cells.